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Smithsonian Magazine

A Psychedelic Compound Found in 'Magic' Mushrooms Might Prevent Debilitating Nerve Damage and Pain Caused by Chemotherapy

A study suggests psilocybin, a compound in magic mushrooms, may protect against nerve damage caused by chemotherapy. Researchers found it prevented pain hypersensitivity in mice and human tissue. They are starting a mid-stage trial to test its effects in people.

What happened

Psilocybin was shown to prevent nerve damage in mice and human tissue when given before chemotherapy. The study found it protected against pain without affecting the cancer drug's effectiveness.

Why it matters

Chemotherapy often causes long-term nerve damage, and this could offer a new way to protect patients. If proven effective, it could improve quality of life for many cancer survivors.

Why it belongs here

The research shows potential for a natural compound to address a serious side effect of treatment, offering hope and a new direction for medical science.

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